85问答库 > 以镰形细胞贫血症为例,说明分子病的发病机理

以镰形细胞贫血症为例,说明分子病的发病机理

2025-03-16 00:46:55
推荐回答（1个）
回答1：

如果我没有记错的话是这样的，他是基因突变引起的，导致红细胞内的某个蛋白的氨基酸变化了，进而影响了蛋白的多聚化，使蛋白的形状改变，影响到细胞的状态，像是肚子里面有东西顶着包膜一样。参考书我记得的，王静岩的生物化学，应该是在血红蛋白，蛋白的高级结构这章，你可以看下，可能是Ala-GLU这样的突变。

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