be good at 是擅长于做某事
be good with是和某人相处的好,相当于get on well with sb.
get along well with sb.
be good at.擅长于做。。
able to do something well
Alex is very good at languages.She's good at making things.
be good with擅长于和。。打交道
He's very good with people (=skilful at dealing with people) .
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